Each year, the European Federation of Medical Informatics (EFMI) holds a Special Topic Conference (STC). In 2023, the main focus is telehealth Ecosystems in Practice and conference topics will include homecare and telemonitoring, televisits, teleradiology, telerehabilitation, data integration and standards, sensors, devices and Patient Reported Outcomes, AI applications to telehealth, healthbots and conversational agents and, finally, embedded decision support systems.